p3P-E.coli expression strains

Those strains are available on the plateforme either as vial of competent cells (column “C”) or as glycerol stocks.

Strain Type Resistance Special feature C Origin
BL21 (DE3) B Classic highly productive strain  yes Novagen
Bl21 (DE3) pLysS B Cm + LysY =repression of leaky expression  yes Novagen
Rosetta2 (DE3) pLysS B Cm 7 rare codons tRNAs for eukaryotic proteins  yes Novagen
Rosetta-gami 2(DE3) pLysS

K-12

Tet + Str + Cm

7 rare codons tRNAs for eukaryotic proteins+ enhances disulfide bond formation  yes Novagen
Rosetta-gami B(DE3) pLysS

B

Kan + Tet + Cm

6 rare codons tRNAs for eukaryotic proteins+ enhances disulfide bond formation+ LacZY mutant (Tuner)  yes Novagen
Rosetta Blue (DE3) pLysS

K-12

Tet + Cm

6 rare codons tRNAs for eukaryotic proteins+recA- , endA- , lacI q ; high transformation efficiency

 yes Novagen
Origami 2(DE3) pLysS

K-12

Tet + Str + Cm

trxB/gor mutant

promote disulfide bond formation

 yes Novagen
Origami B(DE3) pLysS

B

Kan + Tet + Cm

promote disulfide bond formation; LacZY mutant (Tuner)  yes Novagen
SoluBL21 (DE3) B selected evolution for soluble protein expression  yes GenLantis
SoluBL21 (DE3) pLysS B Cm selected evolution for soluble protein expression, pLysS introduced  yes GenLantis
Arctic Express B Gt expression of low Temp adapted chaperone Cpn 60/10  yes Agilent
SHuffle T7 Express   SpcR promote disulfide bond formation  yes NEB
BL21(DE3) pG-KJE8 B Cm dnaK-dnaJ-grpE-groES-groEL chaperones  yes Takara
BL21(DE3) pGro7 B Cm groES-groEL chaperones  yes Takara
BL21(DE3) pKJE7 B Cm dnaK-dnaJ-grpE chaperones  yes Takara
BL21(DE3) pG-Tf2 B Cm groES-groEL-Tig chaperones   Takara
BL21(DE3) pTf16 B Cm tig chaperone  yes Takara
BL21(DE3) pBB530/535 B Cm/Spc GrpE DnaK DnaJ   DeMarco Lab
BL21(DE3) pBB540/535 B Cm/Spc GrpE ClpB DnaK DnaJ   DeMarco Lab
BL21 (DE3)pBB528/541 B Cm/Spc GroESL   DeMarco Lab
BL21 (DE3)pBB540/542 B Cm/Spc GrpE ClpB DnaK DnaJ GroESL (high)   DeMarco Lab
BL21 (DE3)pBB540/550 B Cm/Spc GrpE ClpB DnaK DnaJ GroESL (low)   DeMarco Lab
BL21 (DE3)pBB528/572 B Cm/Amp ibpA/B   DeMarco Lab
BL21 (DE3)pBB528/541/572 B Cm/Spc/Amp ibpA/B GroESL   DeMarco Lab
BL21 (DE3)pBB540/550/572 B Cm/Spc/Amp GrpE ClpB DnaK DnaJ GroESL ibpA/B   DeMarco Lab
Lemo 21 B Cm tunable Expression level with Rhamnose induced LysY  yes NEB
HMS174 K-12   helpfull for toxic proteins   Novagen
NiCo21 (DE3)
B
helpfull to remove contaminating Ecoli proteins during IMAC purif
yes
NEB
BL21AI
B   induction with arabinose (tunable)
yes
Invitrogen

Resistance: in bold= selection must be performed in order to maintain plasmids